4-ethyl-2-methoxyphenyl undec-10-enoate

DOI: 10.14469/hpc/8016 Metadata

Created: 2021-03-22 20:18

Last modified: 2021-03-26 11:50

Author: Murky Liu

License: Creative Commons: Public Domain Dedication 1.0

Funding: (none given)

Description

10-undecenoic acid (1.0 g, 5.5 mmol) was dissolved in acetonitrile (15.5 mL), DMPA (6.1 g, 0.5 mmol) and EDC.HCl (1.2 g, 6.5 mmol), adding to 4-ethylguaiacol (0.7 g, 5 mmol). Reflux was carried for an hour. Hexane (20 mL) was added to the mixture before washing twice with 1 M aqueous HCl (2 x 20 mL, 2 x 20 mmol) After eliminating the aqueous layer, the organic layer was washed twice with 10 wt% sodium bicarbonate (2 x 20 mL, 0.5 x 2 mmol), and once with water (20 mL)， then twice with brine (2 x 20 mL). The organic phase was separated, dried by MgSO4, and evaporated to afford a 0.8 g of colourless oil which is 4-ethyl-2-methoxyphenyl undec-10-enoate. Yield indicated by NMR: ~9%. 1H NMR (ppm, CDCl3)= 6.9, 6.8, 5.9, 5.0, 4.0, 2.5, 2.0, 1.75, 1.45, 1.2; IR (ATR): v(cm-1) = 2926, 1761, 1510, 1270, 1123, 1035.

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4-ethyl-2-methoxyphenyl undec-10-enoate.cdxml 6KB chemical/x-cdxml
ml2620.pdf 31KB application/pdf pdf
ml2620.mnova 620KB chemical/x-mnova mnova
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ml2620.jdx 203KB chemical/x-jcamp-dx jdx
ml2620_PROTON-1-1.jdf 550KB chemical/x-jeol-jdf raw
ml2620_PROTON-1-1.mnpub 0 chemical/x-mnpub Mestrenova signature file for ml2620_PROTON-1-1.jdf

Member of collection / collaboration

DOIDescription
10.14469/hpc/7350 1st Year undergraduate synthesis 1.2 laboratory (2020-2021)

Subject Keywords

KeywordValue
inchi InChI=1S/C20H30O3/c1-4-6-7-8-9-10-11-12-13-20(21)23-18-15-14-17(5-2)16-19(18)22-3/h4,14-16H,1,5-13H2,2-3H3
inchikey NHNNSJKSHGAQCK-UHFFFAOYSA-N

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