2-methoxy-4-methylphenyl pentadecanoate
DOI: 10.14469/hpc/8008 Metadata
Created: 2021-03-21 19:49
Last modified: 2021-03-22 12:55
License: Creative Commons: Public Domain Dedication 1.0
Funding: (none given)
Description
Pentadecanoic Acid (1.33 g, 5.5 mmol) was added to creosole (0.69 g, 5.0 mmol) with acetonitrile (15 mL), DMAP (0.0611 g, 0.5 mmol) and EDC.HCl (1.246, 6.5 mmol) resulting in a colourless solution that was refluxed for 2 hours using TLC to monitor the extent of reaction. An acid/base aqueous/organic work-up followed by washing the refluxed mixture added to hexane (20 mL) with HCl twice (2 x 20 mL, 1M), 10 wt% Sodium Bicarbonate twice (2 x 20 mL), water (20 mL) and saturated aqueous NaCl twice (2 x 20 mL) resulting in the separation of the organic phase, which was subsequently dried using MgSO4, filtered under gravity and evaporated in vacuo to afford a colourless oil. After this oil was allowed to stand, 2-methoxy-4-methylphenyl pentadecanoate acid crystallised in an exothermic reaction releasing heat to form small, white, solid crystals yielding the isolated product: 1.0 g (55.56%, 5 mmol)
Files
| Filename | Size | Type | Description |
|---|---|---|---|
| 2-methoxy-4-methyl-phenyl pentadecanoate.mnova | 472KB | chemical/x-mnova | Analysed NMR Data (MNova File) |
| 2-methoxy-4-methyl-phenyl pentadecanoate.mnpub | 0 | chemical/x-mnpub | Mestrenova signature file for 2-methoxy-4-methyl-phenyl pentadecanoate.mnova |
| 2-methoxy-4-methyl-phenyl pentadecanoate.jdx | 126KB | chemical/x-jcamp-dx | NMR Data (JCAMP File) |
| 2-methoxy-4-methyl-phenyl pentadecanoate.pdf | 36KB | application/pdf | NMR Spectra (PDF File) |
| 2-methoxy-4-methylphenyl pentadecanoate.cdxml | 7KB | chemical/x-cdxml | Molecular Structure (ChemDraw) |
| Files.zip | 1MB | application/zip | Raw NMR Data (Zip File) |
| Files.mnpub | 0 | chemical/x-mnpub | Mestrenova signature file for Files.zip |
Member of collection / collaboration
| DOI | Description |
|---|---|
| 10.14469/hpc/7350 | 1st Year undergraduate synthesis 1.2 laboratory (2020-2021) |
Subject Keywords
| Keyword | Value |
|---|---|
| inchi | InChI=1S/C2H6O.7CH4/c1-3-2;;;;;;;/h1-2H3;7*1H4 |
| inchikey | KGNGJTQLEKAFHA-UHFFFAOYSA-N |