Ï or Ï nucleophilic reactivity of imines?
Created: 2017-08-21 17:42
Last modified: 2017-08-21 17:47
License: Creative Commons: Public Domain Dedication 1.0
Funding: (none given)
Nucleophiles are species that seek to react with an electron deficient centre by donating a lone or a Ï-bond pair of electrons. The ambident variety has two or more such possible sources in the same molecule, an example of which might be hydroxylamine or H2NOH. I previously discussed how for this example, the energetics allow the nitrogen lone pair (Lp) to win out over the O Lp. Here, I play a similar game, but this time setting an NLp up against a Ï-pair.
Member of collection / collaboration
|10.14469/hpc/177||Computation data for Henry Rzepa's blog|
|Current dataset ...||DOI||Description|
|References||10.14469/hpc/2969||Ï or Ï? The ambident nucleophilic reactivity of imines: crystallographic and computational reality checks.|
|References||10.14469/hpc/2970||Ï or Ï nucleophilic reactivity of imines? A mechanistic twist emerges.|
|References||10.14469/hpc/2971||Ï or Ï nucleophilic reactivity of imines? A mechanistic reality check using substituents.|