Kinetic Benchmarking Reveals the Competence of Prenyl Groups in Ring-Closing Metathesis
DOI: 10.14469/hpc/2707 Metadata
Created: 2017-07-07 11:25
Last modified: 2019-04-04 10:02
License: Creative Commons: Public Domain Dedication 1.0
Funding: (none given)
Co-author: D. Christopher Braddock
Description
A series of prenyl-containing malonates were kinetically benchmarked against the standard allyl-containing congeners using a ruthenium benzylidene pre-catalyst for ring-closing metatheses. The prenyl grouping was found to be a superior acceptor olefin compared to an allyl group in RCM processes with ruthenium alkylidenes derived from terminal alkenes. The prenyl group was also found to be a highly competent acceptor for a ruthenium alkylidene derived from a 1,1-disubstituted olefin in a RCM process.
Members
| DOI | Description |
|---|---|
| 10.14469/hpc/2715 | 1H NMR Kinetic Data for Kinetic Benchmarking Reveals the Competence of Prenyl Groups in Ring-Closing Metathesis |
| 10.14469/hpc/2708 | NMR Data for Kinetic Benchmarking Reveals the Competence of Prenyl Groups in Ring-Closing Metathesis |
Associated DOIs
| Current dataset ... | DOI | Description |
|---|---|---|
| References | 10.1021/acs.orglett.7b02492 | Published article: Kinetic Benchmarking Reveals the Competence of Prenyl Groups in Ring-Closing Metathesis |