[CuI(PPh3)3]-Mediated Arylation of 1,2,3-Triazoles
DOI: 10.14469/hpc/14893 Metadata
Created: 2024-12-23 09:22
Last modified: 2025-05-08 14:27
License: Creative Commons: Public Domain Dedication 1.0
Funding: (none given)
Co-author: Jialei Qian Co-author: Matthew Foulkes Co-author: Raul Alberto Pacheco Muino Co-author: Vera Kleene
Description
The arylation of 1,4-disubstituted triazoles with [CuI(PPh3)3] is reported. The reactions were carried out in relatively concentrated solutions of hot DMF in the presence of air and moisture. These conditions were suitable for a range of substrates, specifically triazoles containing a pyridyl group, which are particularly interesting in a diverse applications such as ancillary ligands or bioactive compounds, for instance
Members
| DOI | Description |
|---|---|
| 10.14469/hpc/15055 | 2j: 1-octyl-4-phenyl-1H-1,2,3-triazole |
| 10.14469/hpc/14922 | 2a: 1-benzyl-5-(4-methoxyphenyl)-4-phenyl-1H-1,2,3-triazole |
| 10.14469/hpc/14934 | 2b: 1-benzyl-4-phenyl-5-(p-tolyl)-1H-1,2,3-triazole |
| 10.14469/hpc/14940 | 2k: 2-(1-benzyl-5-(4-methoxyphenyl)-1H-1,2,3-triazol-4-yl)pyridine |
| 10.14469/hpc/14935 | 2c: 1-benzyl-4,5-diphenyl-1H-1,2,3-triazole |
| 10.14469/hpc/14936 | 2d: 1-benzyl-5-(naphthalen-1-yl)-4-phenyl-1H-1,2,3-triazole |
| 10.14469/hpc/14937 | 2e: 1-benzyl-5-(4-chlorophenyl)-4-phenyl-1H-1,2,3-triazole |
| 10.14469/hpc/14946 | 2r: 3-(1-benzyl-5-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)pyridine |
| 10.14469/hpc/14938 | 2g: 6-(4-phenyl-5-(p-tolyl)-1H-1,2,3-triazol-1-yl)hexanenitrile |
| 10.14469/hpc/14939 | 2h: 6-(5-(4-methoxyphenyl)-4-phenyl-1H-1,2,3-triazol-1-yl)hexanenitrile |
| 10.14469/hpc/14945 | 2q: 3-(1-benzyl-5-(naphthalen-1-yl)-1H-1,2,3-triazol-4-yl)pyridine |
| 10.14469/hpc/14944 | 2p: 3-(1-benzyl-5-(p-tolyl)-1H-1,2,3-triazol-4-yl)pyridine |
| 10.14469/hpc/14943 | 2n: 2-(1-benzyl-5-(4-chlorophenyl)-1H-1,2,3-triazol-4-yl)pyridine |
| 10.14469/hpc/14942 | 2m: 2-(1-benzyl-5-(naphthalen-1-yl)-1H-1,2,3-triazol-4-yl)pyridine |
| 10.14469/hpc/14941 | 2l: 2-(1-benzyl-5-(p-tolyl)-1H-1,2,3-triazol-4-yl)pyridine |
Associated DOIs
| Current dataset ... | DOI | Description |
|---|---|---|
| References | 10.1002/cctc.202500111 | Published article |