NMR data for compound 14. N-benzyl-2-(2-chlorophenyl)-2-hydroxyacetamide

DOI: 10.14469/hpc/14720 Metadata

Created: 2024-11-01 15:26

Last modified: 2024-11-05 18:12

Author: Henry Rzepa

License: Creative Commons: Public Domain Dedication 1.0

Funding: (none given)

Description

Synthesised according to the general procedure, with 40 hours reaction time. Purified by flash column chromatography (EtOAc : Hexanes 30 à 70 %). Yield = 638 mg white solid, 2.32 mmol, 46%. Analytical data is in accordance with literature values.11 1H NMR (700 MHz, CDCl3): δ (ppm) = 7.47 (dd, J = 7.7, 1.8 Hz, 1H), 7.38 (dd, J = 7.8, 1.3 Hz, 1H), 7.30 (m, 3H), 7.26 (m, 2H), 7.17 (d, J = 7.8 Hz, 2H), 6.55 (br s, 1H), 5.55 (d, J = 4.6 Hz, 1H), 4.51 (dd, J = 14.9, 5.9 Hz, 1H), 4.42 (dd, J = 14.9, 5.8 Hz, 1H), 4.10 (d, J = 4.6 Hz, 1H). 13C NMR (176 MHz, DMSO-d6): δ (ppm) = 171.3, 139.6, 139.1, 132.7, 129.3, 129.2, 129.0, 128.2, 127.3, 127.1, 126.7, 70.5, 42.0. HRMS [C15H14ClNO2 + H+] : Calculated 276.0786, observed 276.0789 Melting point: 81 – 84 °C

Member of collection / collaboration

DOIDescription
10.14469/hpc/14635 Borate-Catalysed Direct Amidation Reactions of Coordinating Substrates. NMR data

Members

DOIDescription
10.14469/hpc/14769 NMR data for compound 14. N-benzyl-2-(2-chlorophenyl)-2-hydroxyacetamide. 1H
10.14469/hpc/14770 NMR data for compound 14. N-benzyl-2-(2-chlorophenyl)-2-hydroxyacetamide. 13C.

Subject Keywords

KeywordValue
Inchi InChI=1S/C15H14ClNO2/c16-13-9-5-4-8-12(13)14(18)15(19)17-10-11-6-2-1-3-7-11/h1-9,14,18H,10H2,(H,17,19)
Inchikey RAWFHCCJOFULFP-UHFFFAOYSA-N

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