Simulation results spin-labelled liposomes							
							
tau_c	rotational correlation time							
S_zz	segmental order parameter
tau_f	fluorescence lifetime							
g_iso	isotropic g-value							
a_iso	apparent isotropic hyperfine coupling							
eta		viscosity 													
	
	
Fit data sets (linear fits in Figure S6)							
						mean				Std. Dev.			
Probe		Parameter	Intercept	Slope	Intercept	Slope		
5-DSPC		tau_c		-0.578		0.622	0.078		0.045		
			S_zz		-0.356		0.074	0.007		0.004		
12-DSPC		tau_c		-0.793		0.675	0.122		0.070		
			S_zz		-0.676		0.094	0.006		0.003		
16-DSPC		tau_c		-1.235		0.740	0.085		0.049		
			S_zz		-1.229		0.262	0.012		0.007		
C10-BODIPY	tau_f		-0.719		0.446	0.024		0.010		
							

Results from EPR simulations													
16-DSPC				g_iso	a_iso in MHz	tau_c in ns	S_zz	mean eta-values in mPas		
																from tau_c	from S_zz	average
Liposome							
No ROS				2.0061	40.01			2.13		0.211	129.6		128.6		129.1
Hydrogen Peroxide	2.0060	40.17			1.99		0.208	118.1		122.7		120.4
Hydroxyl Radical	2.0060	40.07			1.99		0.208	118.2		122.5		120.4
PLs														
No ROS				2.0061	39.93			2.09		0.208	126.3		122.5		124.4
Superoxide Radical	2.0060	40.03			2.07		0.208	124.7		122.5		123.6
Hydrogen Peroxide	2.0060	40.10			2.02		0.208	120.7		122.5		121.6
Hydroxyl Radical	2.0060	40.10			2.02		0.208	120.7		122.5		121.6
							
12-DSPC				g_iso	a_iso in MHz	tau_c in ns	S_zz	mean eta-values in mPas	
																from tau_c	from S_zz	average
Liposome							
No ROS				2.0060	40.33			4.72		0.341	149.0		166.3		157.6
Hydrogen Peroxide	2.0059	40.50			4.65		0.339	145.8		156.2		151.0
Hydroxyl Radical	2.0059	40.40			4.39		0.339	133.8		156.2		145.0
PLs													
No ROS				2.0061	40.17			4.78		0.341	151.8		166.3		159.0
Superoxide Radical	2.0060	40.40			4.78		0.341	151.8		166.3		159.0
Hydrogen Peroxide	2.0060	40.40			4.39		0.339	133.8		156.2		145.0
Hydroxyl Radical	2.0060	40.33			4.39		0.339	133.8		156.2		145.0
							
5-DSPC				g_iso	a_iso in MHz	tau_c in ns	S_zz	mean eta-values in mPa		
																from tau_c	from S_zz	average
Liposome							
No ROS				2.0060	41.33			6.74		0.652	182.6		191.2		186.9
Hydrogen Peroxide	2.0059	41.33			6.51		0.652	172.5		191.2		181.9
Hydroxyl Radical	2.0059	41.33			6.51		0.652	172.5		191.2		181.9
PLs												
No ROS				2.0060	41.17			6.85		0.652	187.4		191.2		189.3
Superoxide Radical	2.0059	41.37			6.85		0.652	187.4		191.2		189.3
Hydrogen Peroxide	2.0059	41.37			6.49		0.650	171.8		183.5		177.7
Hydroxyl Radical	2.0059	41.37			6.49		0.650	171.8		183.5		177.7
							
							
Results from TCSPC simulations							
							
							tau_f in ns		eta in mPas					
Liposomes									mean	SD				
No ROS						1.83			158.7	10.5				
Hydrogen peroxide (low)		1.80			152.9	10.0				
Hydroxyl radical (low)		1.78			149.1	10.9				
Hydrogen peroxide (high)	1.81			154.8	10.1				
Hydroxyl radical (high)		1.80			152.9	10.2				
PLs							
No ROS						1.84			160.6	10.5				
Superoxide radical			1.79			151.0	10.1				
Hydrogen peroxide			1.78			149.1	10.0				
Hydroxyl radical			1.81			154.8	10.8