4-formyl-2,6-dimethoxyphenyl 2-(4-methoxyphenyl)acetate
DOI: 10.14469/hpc/10176 Metadata
Created: 2022-03-01 14:42
Last modified: 2022-03-01 18:00
License: Creative Commons: Public Domain Dedication 1.0
Funding: (none given)
Description
Syringaldehyde (0.91 g, 5.0 mmol) was dissolved in acetonitrile (35 mL) with catalyst DMAP (0.06 g, 0.5 mmol) and EDC.HCl (1.25 g, 6.5 mmol). 4-methoxyphenylacetic acid (0.92 g, 5.5 mmol) was then added to the solution and heated to reflux. Upon completion of the reaction, hexane (20 mL) was added to the mixture, and the mixture was then extracted using HCl (20 mL, 1 M), sodium bicarbonate (20 mL, 10 wt%), water (20 mL), saturated sodium chloride (20 mL), and dried with MgSO4. The solvent was then removed in vacuo and gave the product of white, translucent crystals (0.22 g, 0.67 mmol, 13 % yield).
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Member of collection / collaboration
| DOI | Description |
|---|---|
| 10.14469/hpc/8679 | 1st Year undergraduate synthesis 1.2 laboratory (2021-2022) |
Subject Keywords
| Keyword | Value |
|---|---|
| inchi | InChI=1S/C18H18O6/c1-21-14-6-4-12(5-7-14)10-17(20)24-18-15(22-2)8-13(11-19)9-16(18)23-3/h4-9,11H,10H2,1-3H3 |
| inchikey | GTLIMLTYVRBPEP-UHFFFAOYSA-N |